© 2021 American Society for Veterinary Clinical Pathology. Significant (P < 0.05) constant or proportional bias was found for many analytes for all three method comparison studies.ĭue to the presence of statistically significant differences between all three analyzers that may be clinically relevant, it is recommended that reference intervals be created for new blood gas analyzers, even when similar methodologies are used.īlood gas analyzers canine clinical chemistry method comparison. Enzymatic Immuno Inhibition in Beckman Coulter AU680. Up to 705.0 mg/dl 20-700 mg/dl 11 Blood (Serum) HDL Cholesterol Accelerator selective detergent in Alinity Ci. Passing-Bablok regression and Bland-Altman plots were used for method comparison. 0.28-44.40 mmol/L 0.6-45 mmol /L 10 Blood (Serum) Total Cholesterol Enzymatic method in Alinity Ci CHO-POD in Beckman Coulter AU680. Results for serum chloride, potassium, sodium, creatinine, urea nitrogen, and L-lactate concentrations obtained from the Prime Plus VET and Ultra analyzers were compared. Results for serum chloride, potassium, sodium, creatinine, and urea nitrogen concentrations obtained from the Prime Plus VET and Ultra analyzers were compared with results from the Beckman analyzer, which was considered to be a reference method. Jugular venous blood samples were collected from 103 endurance-trained sled dogs, and serum was harvested and stored for analysis.

We hypothesized that the three analyzers would be identical within inherent imprecision.

We aimed to perform method comparison studies to evaluate selected canine serum biochemical values obtained using the Nova Stat Profile Prime Plus VET (Prime Plus VET), Stat Profile Nova pHOx Ultra (Ultra), and Beckman Coulter AU680 (Beckman) analyzers. This could suggest the use of separate reference intervals and, thus, has implications when making clinical decisions. However, results may not be comparable between blood gas chemistry analyzers and reference chemistry analyzers or between different models of blood gas chemistry analyzers. Blood gas chemistry analyzers typically produce results faster and use smaller sample volumes than reference chemistry analyzers.

Beckman coulter au680